Can 21st Century Vitamin D3 Help with Skin Cancer?
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 12 Reviews
8.4
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol)
50 mcg (2,000 IU)
250%
Top Medical Research Studies
8
Vitamin D's effect on BCC treatment
A Clinical Trial to Determine the Impact of Tumor Size, Histological Subtype, and Vitamin D Status on the Therapeutic Response of Basal Cell Carcinoma to Photodynamic Therapy.
We conducted a clinical trial to understand how vitamin D might impact skin cancer treatment, specifically targeting basal cell carcinoma (BCC). In our study, 35 patients participated in an innovative approach where they received three sessions of photodynamic therapy (PDT) using a special light, after either taking high-dose vitamin D, a placebo, or having no pretreatment at all.
Using advanced 3D photography, we monitored the tumors throughout the treatment. We found that 70% of tumors cleared after PDT, but those that didn't respond often had aggressive histologic subtypes. Interestingly, the effectiveness of vitamin D seemed to relate to the tumor's depth. Among the tumors analyzed, thinner ones showed a 65% chance of responding to vitamin D, while thicker tumors had a much lower response rate of just 28%.
Overall, we discovered that vitamin D may be a beneficial supplement in enhancing the effects of PDT for suitable BCC lesions. These findings suggest a promising potential role for vitamin D in skin cancer therapy, making it an encouraging avenue for future exploration.
Read More
Most Useful Reviews
9
Increased immunity
1 people found this helpful
Excellent! I took several months before writing this review to assess the results. Following an analysis, my vitamin D levels have improved, which is encouraging. I purchased a large jar at a great price for the family. Vitamin D is vital for muscle tone and boosting immunity; it also supports the thyroid gland, aids in blood clotting, and helps in maintaining nerve sheaths while regulating blood pressure. Iโm pleased to recommend it! ๐
Read More
9
Reduced pain
I ordered this for my 5-year-old daughter, who has juvenile arthritis, with a daily dosage of 2000 mcg. Initially, there wasn't much change, and she experienced discomfort in the mornings. However, she is now full of energy and active, which delights me. For adults, the recommended dosage is 5000 mcg. We took it for six months and were advised to stick to the maximum dosage for better effects. Happy with our results!
Read More
9
Joint pain relief
A good supplement! This year, my whole family started taking vitamin D for the first time. Since then, our joint pain has disappeared, and I feel much better overall.
A Clinical Trial to Determine the Impact of Tumor Size, Histological Subtype, and Vitamin D Status on the Therapeutic Response of Basal Cell Carcinoma to Photodynamic Therapy.
We conducted a clinical trial to understand how vitamin D might impact skin cancer treatment, specifically targeting basal cell carcinoma (BCC). In our study, 35 patients participated in an innovative approach where they received three sessions of photodynamic therapy (PDT) using a special light, after either taking high-dose vitamin D, a placebo, or having no pretreatment at all.
Using advanced 3D photography, we monitored the tumors throughout the treatment. We found that 70% of tumors cleared after PDT, but those that didn't respond often had aggressive histologic subtypes. Interestingly, the effectiveness of vitamin D seemed to relate to the tumor's depth. Among the tumors analyzed, thinner ones showed a 65% chance of responding to vitamin D, while thicker tumors had a much lower response rate of just 28%.
Overall, we discovered that vitamin D may be a beneficial supplement in enhancing the effects of PDT for suitable BCC lesions. These findings suggest a promising potential role for vitamin D in skin cancer therapy, making it an encouraging avenue for future exploration.
Read More
User Reviews
USERS' SCORE
Good
Based on 12 Reviews
8.4
All Reviews
Positive Reviews
Negative Reviews
9
Increased immunity
1 people found this helpful
Excellent! I took several months before writing this review to assess the results. Following an analysis, my vitamin D levels have improved, which is encouraging. I purchased a large jar at a great price for the family. Vitamin D is vital for muscle tone and boosting immunity; it also supports the thyroid gland, aids in blood clotting, and helps in maintaining nerve sheaths while regulating blood pressure. Iโm pleased to recommend it! ๐
Read More
9
Reduced pain
I ordered this for my 5-year-old daughter, who has juvenile arthritis, with a daily dosage of 2000 mcg. Initially, there wasn't much change, and she experienced discomfort in the mornings. However, she is now full of energy and active, which delights me. For adults, the recommended dosage is 5000 mcg. We took it for six months and were advised to stick to the maximum dosage for better effects. Happy with our results!
Read More
9
Joint pain relief
A good supplement! This year, my whole family started taking vitamin D for the first time. Since then, our joint pain has disappeared, and I feel much better overall.
Read More
9
Clear skin
Works well! My husband and I take one capsule all year, except in summer. Previously, he had acne on his back during winter, but that problem has disappeared since using this vitamin. The tablets are small and convenient to take.
Read More
9
Quality prevention
Excellent vitamin D, high quality, and conveniently small capsules. I took it for prevention with a small dosage, and I believe this vitamin performed its task well.
Skin cancer is a type of cancer that develops in the skin's cells, often due to exposure to ultraviolet (UV) radiation from the sun or tanning beds. It is the most common form of cancer in the United States, with various types impacting individuals differently. The three primary forms of skin cancer are basal cell carcinoma, squamous cell carcinoma, and melanoma. Basal cell carcinoma, the most common type, usually appears as a small, waxy bump, while squamous cell carcinoma often manifests as a firm, red nodule or a flat sore that doesn't heal. Melanoma, the deadliest form, can appear as a new or changing mole and requires prompt medical attention.
Prevention and early detection are critical in managing skin cancer. Regularly checking your skin for changes and visiting a dermatologist for professional evaluations can help identify issues early on. Wearing sunscreen, protective clothing, and avoiding peak sun exposure times are recommended measures to minimize risk. If you notice any unusual changes in your skin, it’s essential to consult a healthcare professional for a thorough examination and possible biopsy. Remember, early treatment significantly increases the effectiveness of combating skin cancer.
Vitamin D is a fat-soluble vitamin that's essential for maintaining healthy bones and teeth, supporting immune system function, and facilitating normal cell growth and development. It plays a crucial role in calcium absorption in the gut, which is vital for bone health. Unlike most vitamins, our bodies can produce Vitamin D when exposed to sunlight, specifically UVB rays, which is why it’s often referred to as the "sunshine vitamin." However, depending on your geographical location, lifestyle, and skin type, getting sufficient Vitamin D from the sun alone can be challenging, particularly during the winter months.
In addition to sunlight, Vitamin D can be obtained from certain foods such as fatty fish (like salmon and mackerel), fish liver oils, and fortified foods like milk and cereals. Some individuals may also consider supplements, especially if they're at risk for deficiency. Insufficient vitamin D levels are linked to various health issues, including rickets in children, osteomalacia in adults, and even an increased risk of chronic diseases. Regularly checking your vitamin D levels and consulting with a healthcare professional can help ensure you're meeting your needs for optimal health.
Based on user reviews, the timeframe to start seeing results from taking vitamin D supplements can vary significantly. Several users have reported positive changes after a few months of consistent usage. For instance, one user mentioned it took several months of assessment to notice an improvement in their vitamin D levels and overall health Read Review. Another user reported noticeable benefits after six months of use, indicating a longer duration may be necessary for some individuals Read Review.
Additionally, improvements in skin health have been noted by users as well. One review specifically highlighted that after a period of consistent supplementation, the skin on their daughters' hands became much softer and healthier Read Review. Overall, while some users noticed benefits sooner, a general consensus suggests that continued use over several months may yield significant improvements.
Scientific research indicates that vitamin D may play a beneficial role in the treatment of skin cancer, particularly in enhancing the effectiveness of photodynamic therapy (PDT) for basal cell carcinoma (BCC). A clinical trial involving 35 participants demonstrated that after receiving high-dose vitamin D along with PDT, 70% of tumors cleared, particularly those that were thinner. In fact, thinner tumors showed a significantly higher response rate of 65% when vitamin D was part of the treatment regimen, compared to just 28% for thicker tumors. These findings suggest that vitamin D could potentially enhance treatment outcomes in certain cases of skin cancer [1].
While these results are promising, it's important to note that further research is necessary to fully establish the role of vitamin D in skin cancer management. The current data indicates that vitamin D may not only improve the effectiveness of existing therapies but also pave the way for future exploration into its use as a complementary treatment in skin oncology. Therefore, individuals interested in this supplement for skin cancer treatment should stay updated on ongoing research and consult healthcare professionals before making any decisions [1].
Based on user reviews, many individuals have reported substantial improvements in various symptoms after taking vitamin D supplements. For instance, one user noted a significant increase in energy levels, allowing them to feel more active and engaged after suffering through mornings of discomfort previously Read Review. Others have experienced a complete disappearance of joint pain, suggesting that the supplement may play a role in alleviating discomfort associated with such conditions Read Review.
In addition to physical health, users have reported enhancements in skin vitality, with one review mentioning remarkable improvements in the texture of their daughters’ skin, transforming it from very dry to notably softer and healthier Read Review. Furthermore, one person remarked on the positive effects related to acne issues, emphasizing how their condition had significantly improved since starting supplementation Read Review. While individual results can vary, the overall sentiment points towards a favorable impact on health, from energy levels to skin and joint comfort.
Based on user reviews, the appropriate dosage of Vitamin D for treating skin issues, including potential connections to skin cancer, varies considerably, but users seem to agree on a higher intake for adults. One user recommends a dosage of 5000 IU for adults during specific seasons, such as autumn and spring, while noting an improvement in energy, skin, and hair health since starting the supplement Read Review. Another review mentions a prescription for a 2000 mcg dosage for a child with juvenile arthritis, suggesting that this dosage may also be beneficial for skin health Read Review.
While these specific dosages are mentioned, users also caution the importance of personalizing the intake based on individual health needs and doctor's recommendations. Some reports indicate that higher dosages may produce better effects, particularly in the context of managing symptoms Read Review. Ultimately, it's advisable for users to consult with healthcare professionals to determine the best dosage for their personal health circumstances, especially when considering vitamin D for skin cancer treatment.
9
Increased immunity
1 people found this helpful
Excellent! I took several months before writing this review to assess the results. Following an analysis, my vitamin D levels have improved, which is encouraging. I purchased a large jar at a great price for the family. Vitamin D is vital for muscle tone and boosting immunity; it also supports the thyroid gland, aids in blood clotting, and helps in maintaining nerve sheaths while regulating blood pressure. Iโm pleased to recommend it! ๐
9
Reduced pain
I ordered this for my 5-year-old daughter, who has juvenile arthritis, with a daily dosage of 2000 mcg. Initially, there wasn't much change, and she experienced discomfort in the mornings. However, she is now full of energy and active, which delights me. For adults, the recommended dosage is 5000 mcg. We took it for six months and were advised to stick to the maximum dosage for better effects. Happy with our results!
7.5
Softer skin
I gave this to my daughters as prescribed by the endocrinologist. Although we haven't done a follow-up analysis yet, I can already see positive changes. Their skin on their hands and elbows, which used to be very dry, is now much softer and healthier.
9
Joint pain relief
A good supplement! This year, my whole family started taking vitamin D for the first time. Since then, our joint pain has disappeared, and I feel much better overall.
9
Clear skin
Works well! My husband and I take one capsule all year, except in summer. Previously, he had acne on his back during winter, but that problem has disappeared since using this vitamin. The tablets are small and convenient to take.
7.5
Improved health
2 people found this helpful
The most vital vitamin! Iโve been taking it regularly, and my whole family agrees itโs essential for our overall health. It's crucial for the healthy growth of bones and teeth and supports the immune system. I recommend a dosage of 5000 IU for adults in autumn and spring, while my teenage child takes 2000 ME. Since taking this vitamin, my energy levels have significantly increased, and Iโve also noticed improvements in my skin and hair. Wishing everyone good health! ๐
8
Vitamin D's effect on BCC treatment
A Clinical Trial to Determine the Impact of Tumor Size, Histological Subtype, and Vitamin D Status on the Therapeutic Response of Basal Cell Carcinoma to Photodynamic Therapy.
We conducted a clinical trial to understand how vitamin D might impact skin cancer treatment, specifically targeting basal cell carcinoma (BCC). In our study, 35 patients participated in an innovative approach where they received three sessions of photodynamic therapy (PDT) using a special light, after either taking high-dose vitamin D, a placebo, or having no pretreatment at all.
Using advanced 3D photography, we monitored the tumors throughout the treatment. We found that 70% of tumors cleared after PDT, but those that didn't respond often had aggressive histologic subtypes. Interestingly, the effectiveness of vitamin D seemed to relate to the tumor's depth. Among the tumors analyzed, thinner ones showed a 65% chance of responding to vitamin D, while thicker tumors had a much lower response rate of just 28%.
Overall, we discovered that vitamin D may be a beneficial supplement in enhancing the effects of PDT for suitable BCC lesions. These findings suggest a promising potential role for vitamin D in skin cancer therapy, making it an encouraging avenue for future exploration.
References
Maytin EV, Zeitouni NC, Updyke A, Negrey J, Shen AS, et al. A Clinical Trial to Determine the Impact of Tumor Size, Histological Subtype, and Vitamin D Status on the Therapeutic Response of Basal Cell Carcinoma to Photodynamic Therapy. medRxiv. 2025. doi:10.1101/2025.01.30.25321144